anti ang2 antibodies  (R&D Systems)

Journal: Biomedicines

Article Title: Differential Impact of Tumor Endothelial Angiopoietin-2 and Podoplanin in Lymphatic Endothelial Cells on HCC Outcomes with Tyrosine Kinase Inhibitor Treatment According to Sex

doi: 10.3390/biomedicines12071424

Figure Lengend Snippet: Comparison of Ang2, podoplanin, and CLEC-2 staining in female and male patients treated with TKIs (50 µm scale bar). ( A ) 63× image of Ang2 staining in tumor and endothelial tissue (red arrows for endothelia) of a female patient. ( B ) 63× image of Ang2 staining in tumor and endothelial tissue (red arrows for endothelia) of a male patient. ( C ) 63× image of podoplanin staining at the level of the lymphatic endothelium in a female patient. ( D ) 63× image of podoplanin staining at the level of the lymphatic endothelium in a male patient. ( E ) 63× image of CLEC-2 staining at the level of tumor tissue in a female patient. ( F ) 63× image of CLEC-2 staining at the level of tumor tissue in a male patient.

Article Snippet: Sections were then incubated with goat anti-Ang2 primary antibody (AF623, R&D Systems, Inc., Minneapolis, MN, USA) at working dilution of 1:50 or mouse anti-podoplanin primary antibody (05463645001, Roche Diagnostics, Monza, MB, Italy), or rabbit anti-CLEC-2 primary antibody (LSB12627, LifeSpan BioSciences, Inc., Shirley, MA, USA) at working dilution of 1:50.

Techniques: Comparison, Staining

Journal: Biomedicines

Article Title: Differential Impact of Tumor Endothelial Angiopoietin-2 and Podoplanin in Lymphatic Endothelial Cells on HCC Outcomes with Tyrosine Kinase Inhibitor Treatment According to Sex

doi: 10.3390/biomedicines12071424

Figure Lengend Snippet: Ang2, podoplanin, and CLEC-2 staining intensity (expressed as optical density (OD)) in HCC patients treated with TKIs stratified according to sex.

Article Snippet: Sections were then incubated with goat anti-Ang2 primary antibody (AF623, R&D Systems, Inc., Minneapolis, MN, USA) at working dilution of 1:50 or mouse anti-podoplanin primary antibody (05463645001, Roche Diagnostics, Monza, MB, Italy), or rabbit anti-CLEC-2 primary antibody (LSB12627, LifeSpan BioSciences, Inc., Shirley, MA, USA) at working dilution of 1:50.

Techniques: Staining

Journal: Biomedicines

Article Title: Differential Impact of Tumor Endothelial Angiopoietin-2 and Podoplanin in Lymphatic Endothelial Cells on HCC Outcomes with Tyrosine Kinase Inhibitor Treatment According to Sex

doi: 10.3390/biomedicines12071424

Figure Lengend Snippet: Receiver operating characteristic (ROC) curve analysis to evaluate the diagnostic power of the LEC podoplanin ( A ) and of endothelial Ang2 ( B ) to predict extra-hepatic spread. The area under the ROC curves (AUCs) was analyzed using the Hanley and McNeil method . The AUC values were 0.839 (95% CI 0.679 to 0.999; p < 0.0001) and 0.821 (95% CI 0.652 to 0.989; p < 0.0001).

Article Snippet: Sections were then incubated with goat anti-Ang2 primary antibody (AF623, R&D Systems, Inc., Minneapolis, MN, USA) at working dilution of 1:50 or mouse anti-podoplanin primary antibody (05463645001, Roche Diagnostics, Monza, MB, Italy), or rabbit anti-CLEC-2 primary antibody (LSB12627, LifeSpan BioSciences, Inc., Shirley, MA, USA) at working dilution of 1:50.

Techniques: Diagnostic Assay

Journal: Biomedicines

Article Title: Differential Impact of Tumor Endothelial Angiopoietin-2 and Podoplanin in Lymphatic Endothelial Cells on HCC Outcomes with Tyrosine Kinase Inhibitor Treatment According to Sex

doi: 10.3390/biomedicines12071424

Figure Lengend Snippet: Univariate and multivariate Cox regression analysis for survival.

Article Snippet: Sections were then incubated with goat anti-Ang2 primary antibody (AF623, R&D Systems, Inc., Minneapolis, MN, USA) at working dilution of 1:50 or mouse anti-podoplanin primary antibody (05463645001, Roche Diagnostics, Monza, MB, Italy), or rabbit anti-CLEC-2 primary antibody (LSB12627, LifeSpan BioSciences, Inc., Shirley, MA, USA) at working dilution of 1:50.

Techniques: Biomarker Discovery

Journal: Heart rhythm

Article Title: Biomarkers to Predict Improvement of Left Ventricular Ejection Fraction after Atrial Fibrillation Ablation.

doi: 10.1016/j.hrthm.2024.04.044

Figure Lengend Snippet: Figure 1: A: Receiver operator curves of a Biomarker Panel (ANG2, GDF 15, FGF23, MyBPC3) B: Receiver operator curves of the 534

Article Snippet: ANG2 Human Angiopoietin2 / ANG2 ELISA Kit PicoKineTM 5.2$ https://www.bosterbio.com/ 2.

Techniques: Biomarker Discovery